代表性论文

•  Zhou, C.,Sun, Y., Yan, R., Liu, Y., Zuo, E., Gu, C., Han, L., Wei Y., Zeng, R., Li, Y.(*), Zhou H.(*), Guo F.(*), Yang H.(*) (2019) Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis Nature 517: 275-278
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•  Yao, X.*, Zhang, M., Wang, X., Ying, W., Hu, X., Dai, P., Meng, F., Shi, L., Sun, Y., Yao, N., Zhong, W., Li, Y., Wu, K., Li, W.*, Chen, Z.*, Yang, H.* (2018) Tild-CRISPR allows for efficient and precise gene knockin in mouse and human cells Dev. Cell 45: 526-536
•  Zuo, E.W., Huo, X.N., Yao, X., Hu, X.D., Sun, Y.D., Yin, J.H., He, B.B., Wang, X., Shi, L.Y., Ping, J., Wei, Y., Ying, W.Q., Wei, W., Liu, W.J., Tang, C., Li, Y.X., Hu, J.Z.* and Yang, H.* (2017) CRISPR/Cas9-mediated targeted chromosome elimination Genome Biol. 18: 224

所有论文

•  Zhou, C.,Sun, Y., Yan, R., Liu, Y., Zuo, E., Gu, C., Han, L., Wei Y., Zeng, R., Li, Y.(*), Zhou H.(*), Guo F.(*), Yang H.(*) (2019) Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis Nature 517: 275-278
•  Zhou, H., Liu, J., Zhou, C., Gao, N., Rao, Z., Li, H., Hu, X., Li, C., Yao, X., Shen, X., Sun, Y., Wei, Y., Liu, F., Ying, W., Zhang, J., Tang, C., Zhang, X., Xu, H., Shi, L., Cheng, L., Huang, P. *, Yang, H.* (2018) In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR/dCas9-activator transgenic mice Nat. Neurosci. 21: 440-446
•  Zuo, E., Sun, Y., Wu, W., Yuan, T., Ying, W., Sun, H., Yuan, L., Steinmetz, L.*, Li, Y.*, Yang, H.* (2019) Cytosine base editor generates substantial off-target single nucleotide variants in mouse embryos Science 364: 289-292
•  Yao, X.*, Zhang, M., Wang, X., Ying, W., Hu, X., Dai, P., Meng, F., Shi, L., Sun, Y., Yao, N., Zhong, W., Li, Y., Wu, K., Li, W.*, Chen, Z.*, Yang, H.* (2018) Tild-CRISPR allows for efficient and precise gene knockin in mouse and human cells Dev. Cell 45: 526-536
•  Yao, X., Wang, X., Liu, J., Shi, L., Huang, P.*, and Yang, H.* (2018) CRISPR/Cas9-mediated targeted integration in vivo using a homology-mediated end joining-based strategy Jove-J Vis. Exp. 133: e56844
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